Use the num-pad to navigate between nodes. 4 and 6 move the cursor left and right. 8 and 2 move the cursor up and down. 5 descends into the selected node.
Use Enter and Escape to toggle between edit mode and navigation mode.
Here are some links to pages that demonstrate the basic features of this screen reader:
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Google
To submit a search, descend into the form node, select the text field, edit its value (use Enter and Escape), and descend into the Submit button.
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MathML Example Page
This W3C page demonstrates one method for representing MathML expressions. This method uses a hierarchy to introduce levels of abstraction which reflects the expression's internal, logical structure. The entire expression is represented at the highest level. Descend into the expression to view its child nodes.